Navigating internal consistencies: a case report on neuropsychological assessment of functional cognitive disorder
DOI:
https://doi.org/10.31117/neuroscirn.v8i4.454Keywords:
Functional cognitive disorder, Dissociative neurological symptom disorder, Functional neurological disorder, Conversion disorder, Neuropsychological assessmentAbstract
Functional Cognitive Disorder (FCD) is a subtype of Functional Neurological Disorder (FND), with diagnostic criteria that have only recently been established in a major disease classification system. Although objective neuropsychological measures are not required for diagnosing FCD, they can provide valuable insights into discrepancies between subjective cognitive complaints, functionality, and objective neuropsychological performance. We present the case of a 51-year-old Malay female with a history of Major Depressive Disorder who developed neurocognitive complaints affecting her occupational and social functioning following the sudden death of her husband. A comprehensive assessment, including neuropsychological testing, brain MRI, and laboratory investigations, was conducted. Neuropsychological evaluation revealed significant impairments across multiple neurocognitive domains. However, the presence of situational and mood-related variability in memory performance, along with an inconsistency between the severity of her objective cognitive impairments and her largely preserved ability to perform instrumental activities of daily living (IADLs), supported a diagnosis of FCD. The diagnosis and management of FCD require a multidisciplinary approach. Clinical neuropsychology plays a crucial role in both diagnosing and understanding FCD by assessing neurocognitive functioning and intrapsychic processes. The use of various psychological instruments can help elucidate the neurocognitive profile of FCD to inform a more comprehensive and individualized management plan.
Downloads
References
American Psychiatric Association. (2022). Diagnostic and Statistical Manual of Mental Disorders (5th ed., text rev.). https://doi.org/10.1176/appi.books.97808904257871
Ball, H. A., McWhirter, L., Ballard, C., Bhome, R., Blackburn, D. J., Edwards, M. J., Fleming, S. M., Fox, N. C., Howard, R., Huntley, J., Isaacs, J. D., Larner, A. J., Nicholson, T. R., Pennington, C. M., Poole, N., Price, G., Price, J. P., Reuber, M., Ritchie, C., Rossor, M. N., … Carson, A. J. (2020). Functional cognitive disorder: dementia's blind spot. Brain, 143(10), 2895–2903. https://doi.org/10.1093/brain/awaa224
Ball, H. A., Swirski, M., Newson, M., Coulthard, E. J., & Pennington, C. M. (2021). Differentiating functional cognitive disorder from early neurodegeneration: A clinic-based study. Brain Sciences, 11(6), 800. https://doi.org/10.3390/brainsci11060800
Bhome, R., Huntley, J. D., Price, G., & Howard, R. J. (2019). Clinical presentation and neuropsychological profiles of functional cognitive disorder patients with and without co-morbid depression. Cognitive Neuropsychiatry, 24(2), 152–164. https://doi.org/10.1080/13546805.2019.1590190
Bora, E., Harrison, B. J., Yücel, M., & Pantelis, C. (2013). Cognitive impairment in euthymic major depressive disorder: a meta-analysis. Psychological Medicine, 43(10), 2017–2026. https://doi.org/10.1017/S0033291712002085
Cabreira, V., Frostholm, L., McWhirter, L., Stone, J., & Carson, A. (2023). Clinical signs in functional cognitive disorders: A systematic review and diagnostic meta-analysis. Journal of Psychosomatic Research, 173, 111447. https://doi.org/10.1016/j.jpsychores.2023.111447
Carmela, M., Irene, P. D., Clara, L., & Catena, S. M. (2020). Cognitive deficits and Rorschach task. Cogent Psychology, 7(1), 1848111. https://doi.org/10.1080/23311908.2020.1848111
Delis, D. C., & Wetter, S. R. (2007). Cogniform disorder and cogniform condition: Proposed diagnoses for excessive cognitive symptoms. Archives of Clinical Neuropsychology, 22(5), 589–604. https://doi.org/10.1016/j.acn.2007.04.001
Frederickson, J. J., Messina, I., & Grecucci, A. (2018). Dysregulated anxiety and dysregulating defenses: Toward an emotion regulation informed dynamic psychotherapy. Frontiers in Psychology, 9, 2054. https://doi.org/10.3389/fpsyg.2018.02054
Godena, E. J., Freeburn, J. L., Silverberg, N. D., & Perez, D. L. (2023). A case of functional cognitive disorder: Psychotherapy and speech and language therapy insights. Harvard Review of Psychiatry, 31(5), 248–256. https://doi.org/10.1097/HRP.0000000000000379
Haussmann, R., Mayer-Pelinski, R., Borchardt, M., Beier, F., Helling, F., Buthut, M., Meissner, G., Lange, J., Zweiniger, A., & Donix, M. (2018). Extrinsic and intrinsic help-seeking motivation in the assessment of cognitive decline. American Journal of Alzheimer's Disease and Other Dementias, 33(4), 215–220. https://doi.org/10.1177/1533317518755332
Heilbronner, R. L., Sweet, J. J., Morgan, J. E., Larrabee, G. J., Millis, S. R., & Conference Participants1. (2009). American Academy of Clinical Neuropsychology Consensus Conference Statement on the neuropsychological assessment of effort, response bias, and malingering. The Clinical Neuropsychologist, 23(7), 1093–1129. https://doi.org/10.1080/13854040903155063
Kemp, S., Kapur, N., Graham, C. D., & Reuber, M. (2022). Functional cognitive disorder: Differential diagnosis of common clinical presentations. Archives of Clinical Neuropsychology, 37(6), 1158–1176. https://doi.org/10.1093/arclin/acac020
Luca, A., Lo Castro, T., Mostile, G., Donzuso, G., Cicero, C. E., Nicoletti, A., & Zappia, M. (2024). Personality and psychopathological characteristics in functional movement disorders. PLoS ONE, 19(5), e0303379. https://doi.org/10.1371/journal.pone.0303379
McWhirter, L., Ritchie, C., Stone, J., & Carson, A. (2022). Identifying functional cognitive disorder: A proposed diagnostic risk model. CNS Spectrums, 27(6), 754–763. https://doi.org/10.1017/S1092852921000845
Minassian, A., & Perry, M. (2004). The use of projective tests in assessing neurologically impaired populations. In M. J. Hilsenroth, & D. L. Segal (Eds.), Comprehensive handbook of psychological assessment (Vol. 2): Personality assessment (pp. 539 – 552). John Wiley & Sons, Inc.
Pick, S., Goldstein, L. H., Perez, D. L., & Nicholson, T. R. (2019). Emotional processing in functional neurological disorder: A review, biopsychosocial model and research agenda. Journal of Neurology, Neurosurgery, and Psychiatry, 90(6), 704–711. https://doi.org/10.1136/jnnp-2018-319201
Rhee, T. G., Shim, S. R., Manning, K. J., Tennen, H. A., Kaster, T. S., d'Andrea, G., Forester, B. P., Nierenberg, A. A., McIntyre, R. S., & Steffens, D. C. (2024). Neuropsychological assessments of cognitive impairment in major depressive disorder: A systematic review and meta-analysis with meta-regression. Psychotherapy and Psychosomatics, 93(1), 8–23. https://doi.org/10.1159/000535665
Ruggiero, G. M., Spada, M. M., Caselli, G., & Sassaroli, S. (2018). A historical and theoretical review of cognitive behavioral therapies: From structural self-knowledge to functional processes. Journal of Rational-Emotive and Cognitive-Behavior Therapy, 36(4), 378–403. https://doi.org/10.1007/s10942-018-0292-8
Russell, L., Abbass, A., & Allder, S. (2022). A review of the treatment of functional neurological disorder with intensive short-term dynamic psychotherapy. Epilepsy & Behavior, 130, 108657. https://doi.org/10.1016/j.yebeh.2022.108657
Schmidtke, K., Pohlmann, S., & Metternich, B. (2008). The syndrome of functional memory disorder: Definition, etiology, and natural course. The American Journal of Geriatric Psychiatry, 16(12), 981–988. https://doi.org/10.1097/JGP.0b013e318187ddf9
Schroeder, R. W., & Martin, P. K. (2022). Explanations of performance validity test failure in clinical settings. In R. W. Schroeder, & P. K. Martin (Eds.), Validity assessment in clinical neuropsychological practice: Evaluating and managing noncredible performance (pp. 11-30). The Guilford Press.
Semkovska, M., Quinlivan, L., O'Grady, T., Johnson, R., Collins, A., O'Connor, J., Knittle, H., Ahern, E., & Gload, T. (2019). Cognitive function following a major depressive episode: A systematic review and meta-analysis. The Lancet: Psychiatry, 6(10), 851–861. https://doi.org/10.1016/S2215-0366(19)30291-3
Simmonds, J., Constantinides, P., Perry, J. C., Drapeau, M., & Sheptycki, A. R. (2015). Assessing psychodynamic conflict. Psychodynamic Psychiatry, 43(3), 349–377. https://doi.org/10.1521/pdps.2015.43.3.349
Sweet, J. J., Heilbronner, R. L., Morgan, J. E., Larrabee, G. J., Rohling, M. L., Boone, K. B., Kirkwood, M. W., Schroeder, R. W., Suhr, J. A., & Conference Participants (2021). American Academy of Clinical Neuropsychology (AACN) 2021 consensus statement on validity assessment: Update of the 2009 AACN consensus conference statement on neuropsychological assessment of effort, response bias, and malingering. The Clinical Neuropsychologist, 35(6), 1053–1106. https://doi.org/10.1080/13854046.2021.1896036
Van der Hulst, E. J. (Ed.). (2023). A clinician’s guide to functional neurological disorder: A practical neuropsychological approach. Routledge.
Wakefield, S. J., Blackburn, D. J., Harkness, K., Khan, A., Reuber, M., & Venneri, A. (2018). Distinctive neuropsychological profiles differentiate patients with functional memory disorder from patients with amnestic-mild cognitive impairment. Acta Neuropsychiatrica, 30(2), 90–96. https://doi.org/10.1017/neu.2017.21
World Health Organization. (2022). International Classification of Diseases (11th ed.). https://icd.who.int/
Yakin, D., & Arntz, A. (2023). Understanding the reparative effects of schema modes: An in-depth analysis of the healthy adult mode. Frontiers in Psychiatry, 14, 1204177. https://doi.org/10.3389/fpsyt.2023.1204177
Young, J., Arntz, A., Atkinson, T., Lobbestael, J., Weishaar, M., van Vreeswijk, M. & Klokman, J. (2007). Schema Mode Inventory. Schema Therapy Institute. https://doi.org/10.1037/t80759-000
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2025 Siew Chung Mah, Jasmine Elenore Parrott, Zhi Ying Lim, Wei Siong Ng, Hafidah Umar, Muhammad Tahir Khalily, Faiz Mustafar

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The observations and associated materials published or posted by NeurosciRN are licensed by the authors for use and distribution in accord with the Creative Commons Attribution license CC BY-NC 4.0 international, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.