Neuroscience Research Notes: Special Issue on "Epilepsy and Comorbidities"

Epilepsy is a chronic neurological disorder which affects people of all ages. Approximately 70 million people globally are suffering from epilepsy. Nearly 80% of the epileptic population live in low- and middle-income countries. The quality of life is greatly affected by comorbid conditions of epilepsy which include neurological, neurobehavioral and neuropsychiatric disorders.

Comorbidities in epilepsy are common yet ineffectively comprehended and frequently stay unaddressed. The prevalence of comorbid conditions is impressively higher in epilepsy than found in the all-inclusive community and other chronic conditions. There is a wide spectrum of secondary disorders that have a marked impact on the quality of life and burden of the primary epilepsy condition.

The aim of this research topic is to highlight basic, clinical and interdisciplinary research related to epilepsy and its comorbidities. We are pleased to invite Research (Original research)/Technical Notes, Mini Review, Hypothetical Papers and Views (Commentary) articles that summarize current knowledge, and point out gaps in understanding of epilepsy-associated comorbidities and related research for drug discovery. This special topic is focusing on but are not limited to the following specialties:

  • Experimental models of epilepsy and related comorbidities
  • Epilepsy associated neurobehavioral comorbidities like cognitive decline, dementia, anxiety, depression, etc.
  • Mechanisms of epileptogenesis and comorbidities
  • Clinical reports on epilepsy associated neurobehavioral comorbidities
  • Therapeutic and Molecular targets and approaches
Published: 2019-01-31